Graduated in Pharmacy and Biochemistry from the University of São Paulo, and obtained an M.S in Pharmacology from the Escola Paulista de Medicina (EPM) - Unifesp in 1985 and 1989, respectively. In 1992, she joined EPM as a faculty member and after three years got a PhD degree in Pharmacology from the same institution. She conducted two Postdoctoral research periods in US institutions - Thomas Jefferson University (1997) and National Institutes of Health (NIH) (1998-1999) - and in 2005, won the senior professor title from the university. Between 2006 and 2012 she coordinated the graduate program in Pharmacology and as a faculty representative, elected by her peers, took part in Unifesp´s University Council from 2000 to 2012. She was president of Unifesp´s Graduate-Student Association during the 1988-1989 biennium and president of the National Association of Graduate Students in 1989. Between 2001 and 2002, she headed Unifesp’s Faculty Association (Adunifesp) and for two terms he held the vice-presidency position of that same entity. For four years (2004-2008), she served as regional secretary of the Brazilian Society for the Advancement of Science (SBPC), having coordinated the Programme of Science Dissemination (Mário de Andrade Library and public schools). She assumed the regional board of the National Union of Higher-Education Institution Faculty Members (Andes-SN), performing this activity from 2010 to 2012. Her research projects, developed in the areas of Neurosciences and cell death, have been granted funding from major development agencies, including the CNPq - agency from which she receives a 1D productivity scholarship. She is the author of several articles and book chapters within her specialty. Since 2000, she has coordinated the Laboratory of Calcium Signaling and Cell Death and the Multi-User Laboratory of Confocal Microscopy at EPM / Unifesp. In 2004 she joined the Executive Committee (Board of Directors) of the International Society of Cell Death (International Cell Death Society - ICDS). As a member of Unifesp - Plural and Democratic Slate, composing the three-name list presented by the University Council, she was appointed by the Minister of Education for the post of Unifesp’s rector from 2013 to 2017.